Xymelin Extra spray 0.6mg+0.5mg 10ml

Xymelin Extra user manual

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Composition

The composition of the nasal spray includes the basic substances: xylometazoline hydrochloride and ipratropium bromide monohydrate.
Additional constituents: disodium edetate dihydrate, hydrochloric acid, glycerol 85%, sodium hydroxide, purified water.

Form of issue

Produced Xymelin Extra in the form of a nasal spray, packed in plastic bottles of 10 ml.

pharmachologic effect

The spray is characterized by a local vasoconstrictor effect.

Pharmacodynamics and pharmacokinetics

The combined preparation Xymelin Extra includes xylometazoline and ipratropium bromide, which exhibit anticholinergic activity. Also, the drug has a pronounced effect on the secretory activity of the mucous membranes of the nose, compared with non-combined drugs.
At the same time, the development of the effect manifests itself in 3-5 minutes from the moment of use, remaining on average 6-10 hours.
As a result of intranasal use, the drug is almost not absorbed and does not have systemic effects on the body.
The concentration of active components in the blood plasma is very small and practically not determined even by modern methods and studies.

Indications for use

The drug Xymelin Extra is prescribed for treatment:
    acute allergic rhinitis;
    acute respiratory infections accompanied by symptoms of rhinitis or rhinitis;
    Pollinosis;
    sinusitis;
    eustachyte;
    otitis media in order to reduce the swelling of the nasopharyngeal mucosa.
And also during the preparation of patients for various diagnostic procedures in the field of nasal passages.

Contraindications

The use of Xymelin Extra is contraindicated when:
    sensitivity to its components;
    the presence of diseases of the cardiovascular system, for example, arterial hypertension, arrhythmia, tachycardia and atherosclerosis;
    glaucoma;
    atrophic rhinitis;
    hyperthyroidism;
    children up to 2 years;
    lactation, pregnancy.
Also, the drug is not prescribed for patients who have undergone surgery on the meninges, even if they have been carried out for a long time.
Care must be taken in the treatment of patients with diabetes mellitus, prostatic hyperplasia, angina pectoris, obstruction of the bladder neck, cystic fibrosis, impaired intestinal permeability, susceptibility to various bleeding.

Side effects

The use of this drug is usually not accompanied by the development of side effects. However, local reactions should not be excluded in the form of: burning, dryness and irritation of mucous membranes, frequent sneezing. Also, reactions such as dizziness, headaches, visual impairment, sleeping problems, and so on are possible.

Instruction Xymelin Extra (Method and dosage)

As the instruction on the use of the spray indicates, it is used intranasally. Prior to the injection of the drug, the nasal passages are thoroughly cleaned. Duration of treatment and dosage is determined by the doctor, given the complexity of the disease and the individual characteristics of each patient.
Usually, for adults, 1-2 injections per nostril 1-3 times a day are prescribed. On average, the therapeutic course lasts 10 days.

Overdose

Cases of overdose can lead to increased side effects. In this case, treatment is carried out taking into account the manifested symptoms.

Interaction

Joint use of Xymelin Extra and monoamine oxidase inhibitors, as well as tricyclic antidepressants, is unacceptable.
Simultaneous use with anticholinergic drugs can enhance the therapeutic effect of ipratropium bromide.

special instructions

During the treatment period, it is important to keep the dosage and duration of application.
The use of drugs based on xylometazoline, especially in high doses can affect the work of the nervous system. Therefore, it is recommended to abstain from transport management and performing hazardous activities.

Terms of sale

You can buy Xymelin Extra without a prescription.

Storage conditions

To store the spray, the place is not accessible to children, with a temperature of 15-25 ° C.
Shelf life - 2 years.

Reviews of Xymelin Extra

As a rule, the treatment of any cold or ARVI begins with the use of drops for the nose. Modern pharmacology offers a large selection of drugs of this kind, but especially popular are the products created on the basis of xylometazoline. Therefore, reviews about Xymelin Extra are quite common and the opinion about him is very ambiguous.
It is often possible to find discussions about the occurrence of drug dependence. This state develops quite quickly, largely because of the frequent use of drops or spray in higher dosages. Unfortunately, at the beginning of the treatment, many patients try to get rid of the cold as soon as possible, but such carelessness will subsequently require the treatment of drug dependence. According to some users, it took them several years to get rid of it.
As for the treatment of the common cold with the help of Xymelin Extra in compliance with the dosage and therapeutic course, the patients' reviews are mostly positive. The drug helps to quickly and effectively eliminate the manifestations of rhinitis and alleviate the general condition of the sick person.
A separate topic for active discussion is the use of salt solutions and sea water. It should be noted that any vasoconstrictor should be used after thorough cleansing of mucous membranes with the help of these solutions. Some patients use pharmacy products, and someone prepares them themselves. By the way, similar solutions can be used often and in any dosage. It is recommended to use them in the season of colds as prevention. Often this is enough to eliminate the symptoms of rhinitis and prevent the development of the disease.