Dexalgin tabs 25mg #10

Instruction for Dexalgin

Reed more and buy Dexalgin here

Composition

In one tablet of the drug dexketoprofen trometamol 0.0369 g (dexketoprofen 0.025 g) + auxiliary substances (corn starch, glycerin palmitostearate, microcrystalline cellulose, sodium carboxymethyl starch, titanium dioxide, propylene glycol, hypromellose, macrogol 6000).
Dexalgin injection in 1 ampoule contains active active substance (dexketoprofen trometamol 0.0369 g or 0.0738 g) + excipients (sodium chloride, water for injection, ethanol, sodium hydroxide).

Form of issue

Tablets are white, smooth, round and convex, with both sides of the risks. Cardboard packages of 10, 30 and 50 tablets in blisters.
A clear, colorless solution for intramuscular or intravenous administration, 2 ml each in an ampoule. Packages of 1, 5 or 10 pieces.

pharmachologic effect

Anti-inflammatory, antipyretic, analgesic.

Pharmacodynamics and pharmacokinetics

The drug is classified as a non-steroidal anti-inflammatory drug. The active substance dexketoprofen inhibits the cyclooxygenase system and reduces the intensity of prostaglandin synthesis. Thus, after half an hour after taking the drug, the pain subsides and the temperature decreases. The medicine has an anti-inflammatory effect.
When taken orally, reaches a maximum concentration after 40 minutes. The half-life of the kidneys is up to 2 hours. About 99% of the substance binds to blood proteins. With simultaneous intake with food, the maximum concentration in the blood will be somewhat lower and will reach its maximum value longer.
With intravenous and intramuscular administration of drugs, pharmacokinetics is the same as when taking tablets. The maximum concentration is achieved after 10 minutes.

Indications for use

What do tablets Dexalgin? To relieve pain:
    after operations;
    algodismenorea, radiculitis;
    toothache, menstrual pain;
    ischialgia and neuralgia;
    Rheumatoid arthritis, arthrosis, bone metastases, osteochondrosis, spondylitis.
Injections of the drug are prescribed when the use of tablets is impossible or unjustified, for example, in post-operative pain, after serious injuries, with renal colic.

Contraindications

    drug allergy;
    bleeding and gastrointestinal diseases;
    stomach ulcer;
    concurrent treatment with anticoagulants;
    bronchial asthma;
    acute cardiac, renal insufficiency, liver disease;
    pregnant and lactating women, children.

Side effects

Before you buy Dexalgin you should know side effects of the drug.
    nausea and vomiting;
    heart palpitations, increased blood pressure;
    allergic reactions to the skin, rashes, dermatitis, urticaria, chills;
    Anemia, headache, dizziness, fainting, insomnia;
    dry mouth, diarrhea, anorexia, bleeding possible.
When taking a tablet form of the drug, heartburn and discomfort in the stomach are possible.
Injections of Dexalgin may cause fever and pain at the injection site, development of hematoma or inflammation.

Instructions for the use of Dexalgin (Method and dosage)

According to the instructions for Dexalgin in tablets, the dosage of the drug should be prescribed by the doctor individually.
On average, a single dose is half a tablet and should not exceed two tablets (2 to 25 mg). Reception from 2 to 6 times a day. The maximum daily dose of 0,075 grams (3 tablets). Do not take more than five days.
The injections of the drug are given intramuscularly or intravenously, depending on the doctor's recommendation.
Intramuscularly: The ampoule with the drug (2 ml) is injected slowly and deeply. For 50 mg, every 8-12 hours. The maximum daily dose is 0.15 grams. Do not use more than two days.
Intravenous: Dosage, as with intramuscular injection. The medication is administered slowly, at least 15 seconds.
Infusion: In 2 ml of the drug, dilute 100 ml of phys. A solution or a glucose solution. The time of administration is from 15 minutes to half an hour.

Overdose

When an overdose occurs headache, nausea, insomnia, disorientation in space.
Therapy is performed according to the manifested symptoms, it is possible to perform gastric lavage and hemodialysis.

Interaction

Dexalgin 25 (tablets) in combination with salicylates, anticoagulants, ticlopidine, heparin, other NSAIDs, citalopram, low molecular weight heparin preparations, pentoxifylline, sertraline and fluoxetine increases the risk of bleeding.
Use with caution with sulfonamides, methotrexate, lithium preparations, hydantoins due to increased toxic effects on the body. Zidovudine, quinolones, cardiac glycosides, thrombolytics, tsiklosprorin, sulfonylureas and tacrolimus should not be combined with the drug without medical supervision.
The combination with diuretics and ACE inhibitors can cause acute renal failure.
Solution for injection do not mix in a syringe with pethidine, prometezine, hydroxyzine, dopamine, pentazocine. You can mix with morphine, heparin, theophylline and lidocaine.
When mixing the solution for infusion, avoid combination with promethazine and pentazocine. But it is fully compatible with pethidine, dopamine, Hydroxyzine, morphine, heparin, lidocaine, and theophylline.

Storage conditions

Inaccessible to children, dark, cool place. The temperature should not exceed 25-30 degrees.

Shelf life

Tablets are stored for 2 years in the original packaging.
Ampoules of the drug can be stored for 5 years. The prepared solution is 24 hours in a dark place, at a temperature of 3-9 degrees.

With alcohol

It is extremely undesirable to combine with alcohol a drug that has a strong toxic effect on the liver. There may be an increase in side effects.

Reviews about Dexalgin

Reviews on the tablets are good. The drug perfectly removes pain, even very strong and inexpensive. Many keep it in the home medicine cabinet just in case. The disadvantage is the impossibility of long-term use and quite serious side effects.
Reviews about Dexalgin pricks are also good. Helps in a few seconds to get rid of the pain. However, the process itself is quite painful, "cones" can form and then heal for a long time.