Ketonal cream 5% 30gr

Ketonal cream instruction manual

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Ketonal is a drug from a group of non-steroidal anti-inflammatory drugs with pronounced analgesic, decongestant and local antipyretic effect.

Form of issue and composition

Ketonal is available in several dosage forms. Cream Ketonal 5% is a homogeneous thick white mass without foreign impurities and a specific odor. The drug is intended for external use only and is available in aluminum tubes of 30 or 50 g in a cardboard box. The box contains detailed instructions.
The main active ingredient of the cream is Ketoprofen, in 1 g of the drug contains 50 mg of active substance. Also, the composition of the medicine includes auxiliary substances: purified water, magnesium sulfate, white petrolatum, propylene glycol.

Pharmacological properties

Cream Ketonal when applied to the skin surface has a pronounced local anesthetic, warming, anti-edematous and anti-inflammatory effect. Under the influence of the active substance of the drug, the release of enzymes that take an active part in the development of the inflammatory process is blocked.
After applying the agent to the affected area of ​​the skin, the active substance is absorbed to a small extent in the common bloodstream. Even with prolonged use of the cream, Ketoprofen does not adversely affect the condition of the cartilage in the joint.

Indications for use

Cream Ketonal is highly effective when the patient has the following conditions:
    Bechterew's disease;
    Inflammation of the periarticular bag or joint;
    Contusions, sprains, dislocations;
    Muscle pain of various origins;
    Osteochondrosis with pronounced radicular syndrome;
    Psoriatic arthritis;
    Rheumatoid arthritis;
    Radiculitis;
    Pain along the nerve.

Contraindications

Before starting therapy with the drug, the patient should carefully read the attached instructions. The cream has a number of the following contraindications for use:
    Inclination to bleeding, poor coagulability of blood;
    Pregnancy in the 1st and 3rd trimesters;
    Breastfeeding period;
    Age to 14 years;
    Violation of the integrity of the skin - wetting infected eczema, wound surfaces;
    Ulcerative rashes in the areas of application of the drug;
    Individual intolerance;
    Photosensitization reactions in the anamnesis on preparations from the group of nonsteroidal anti-inflammatory drugs.
The drug is not recommended for people who constantly visit the solarium or are forced to stay in direct sunlight for a long time, as this can lead to the development of negative reactions to the active active substance of the cream.

Dosing and Administration

Cream Ketonal can be applied only to the skin, avoiding getting the drug on the mucous membranes. The drug is applied to the previously cleaned dry skin no more than 3 times a day with a thin layer. Cream gently rubbed into the affected area before soaking.
Warming bandage on the wound site can be applied only after complete absorption of the drug, occlusion packs of medicine is not applied to the skin, as this can lead to side effects.
The duration of the course of therapy is determined by the attending physician, however according to the instruction it should not be longer than 14 days. In the absence of the expected effect of the use of Ketonal cream, you should contact a specialist again.

Use in pregnancy and lactation

The use of Ketonal cream in the first trimester is not recommended, since it is not known how safe the active ingredient of the drug for the developing fetus is.
In the 2nd trimester of pregnancy the drug can be used only if the expected benefit for the patient exceeds possible risks for the future baby. Treatment is carried out under the strict supervision of a physician.
The use of 3-trimester cream is contraindicated, since ketoconazole penetrates in small quantities in the blood stream and may lead to the risk of bleeding in women and disturbances from the fetal kidney.
The active substance of the cream can be excreted with the mother's milk, so if you need to treat the drug with a nursing woman, you should consider stopping lactation.

Side effects

Cream Ketonal is well tolerated by patients, but with prolonged use, as well as with increased individual sensitivity, the probability of developing the following adverse reactions increases:
    Local reactions - allergic rash, redness, itching and burning, urticaria, local fever, dermatitis;
    Angioedema;
    In rare cases, the development of anaphylactic shock.

Overdose

With prolonged use of Ketonal cream or applying a thick layer to a large area in patients, development of signs of overdose is possible:
    Hyperemia, mocculation of the skin, development of allergic dermatitis;
    Severe itching of the skin;
    Swelling and burning in the areas where the cream is applied.
With the development of such reactions, the drug is immediately stopped and treated for medical attention.

Interaction of the drug with other drugs

Since the degree of absorption of the active substance cream Ketonal sufficiently low, the existence of any drug interactions with other drugs from the group of nonsteroidal anti-inflammatory is possible only after prolonged and repeated use.
The cream is not recommended to be used concomitantly with other topical agents, which include Ketoprofen or other drugs from the NSAID group.
The drug is not used concomitantly with heparin ointment or other anticoagulants, as it increases the risk of side effects. Patients with hereditary disorders of the blood coagulation system Ketonal cream should be used with extreme caution only after consultation with the physician.

special instructions

The cream is intended only for application to the skin. After each use of the drug, tightly tighten the tube cover and wash hands thoroughly with soap to prevent the medication from entering the eyes. In case of accidental contact with Ketonal, immediately flush with plenty of clean running water and contact the ophthalmologist as soon as possible.
When enough expressed the expected therapeutic effect Ketonal cream can be combined with other dosage forms of the drug - capsules, tablets, suppositories. The daily dose in this case is determined and clearly controlled by the doctor.
After using the drug, to avoid photosensitivity, you should refrain from visiting solariums or staying in direct sunlight for 2 weeks after the end of therapy.
The cream can not be used with occlusive dressings, as this increases the risk of side effects.
Local use of the drug in the form of a cream does not affect the operation of the central nervous system and does not suppress the speed of psychomotor reactions. Applying a cream to treat pathologies in children younger than 14 years is not recommended because of the lack of sufficient information on safety.
Patients with impaired renal or hepatic function do not need a correction of the daily dose of the drug in the form of a cream.

Analogues of Ketonal cream

The following medicinal products are similar in their therapeutic effect with Ketonal cream:
    Voltaren;
    Diclofenac gel;

Leave and storage conditions

Cream Ketonal can be bought in pharmacies without a prescription. Shelf life of the drug is not more than 2 years for this dosage form. Optimal storage temperature should not exceed 25 degrees, protect from children and direct sunlight on the tube.
Do not use the medicine after the expiration date.